Publications

2018

 

 

 

 

 

 

 

 

 

2017

 

 

 

 

2016

 

 

 

2015

 

 

 

 

 

 

 

 

 

 

 

 

 

2014

 

 

 

 

 

 

 

 

 

2013

 

 

 

2012

 

 

 

 

 

 

 

 

 

 

 

 

 

 

2011

 

 

 

 

2009

 

 

 

 

 

 

2008

Targeting myelin lipid metabolism as a potential therapeutic strategy in a model of CMT1A neuropathy.

Fledrich R*, Abdelaal T*, Rasch L, Bansal V, Schütza V, Brügger B, Lüchtenborg C, Prukop T, Stenzel J, Rahman RU, Hermes D, Ewers D, Möbius W, Ruhwedel T, Katona I, Weis J, Klein D, Martini R, Brück W, Müller WC, Bonn S, Bechmann I, Nave KA, Stassart RM* and Sereda MW*

Nat Commun. 2018 in press

 

The axon-myelin unit in development and degenerative disease.

Stassart RM, Möbius W, Nave KA, Edgar JM

Front Neurosci. 2018 in press

 

Dietary cholesterol promotes repair of demyelinated lesions in the adult brain.

Berghoff SA, Gerndt N, Winchenbach J, Stumpf SK, Hosang L, Odoardi F, Ruhwedel T, Böhler C, Barrette B, Stassart RM, Liebetanz D, Dibaj P, Möbius W, Edgar JM, Saher G.

Nat Commun. 2017 Jan 24;8:14241. doi: 10.1038/ncomms14241

 

A New Targeted Model of Experimental Autoimmune Encephalomyelitis in the Common Marmoset.

Stassart RM, Helms G, Garea-Rodríguez E, Nessler S, Hayardeny L, Wegner C, Schlumbohm C, Fuchs E, Brück W.

Brain Pathol. 2016 Jul;26(4):452-64. doi: 10.1111/bpa.12292. Epub 2015 Sep 22.

 

Nerve regeneration: Specific metabolic demands?

Stassart RM, Nave KA.

Exp Neurol. 2015 Jul;269:90-2. doi: 10.1016/j.expneurol.2015.04.002. Epub 2015 Apr 9

 

Neuronal ADAM10 Promotes Outgrowth of Small-Caliber Myelinated Axons in the Peripheral Nervous System.

Meyer zu Horste G, Derksen A, Stassart RM, Szepanowski F, Thanos M, Stettner M, Boettcher C, Lehmann HC, Hartung HP, Kieseier BC.

J Neuropathol Exp Neurol. 2015 Nov;74(11):1077-85. doi: 10.1097/NEN.0000000000000253.

 

Curcumin therapy in a Plp1 transgenic mouse model of Pelizaeus-Merzbacher disease.

Epplen DB, Prukop T, Nientiedt T, Albrecht P, Arlt FA, Stassart RM, Kassmann CM, Methner A, Nave KA, Werner HB, Sereda MW.

Ann Clin Transl Neurol. 2015 Aug;2(8):787-96. doi: 10.1002/acn3.219. Epub 2015 Jun 24.

 

Soluble neuregulin-1 modulates disease pathogenesis in rodent models of Charcot-Marie-Tooth disease 1A.

Fledrich R*, Stassart RM*, Klink A, Rasch LM, Prukop T, Haag L, Czesnik D, Kungl T, Abdelaal TA, Keric N, Stadelmann C, Brück W, Nave KA, Sereda MW.

Nat Med. 2014 Sep;20(9):1055-61. doi: 10.1038/nm.3664. Epub 2014 Aug 24.

 

Progesterone antagonist therapy in a Pelizaeus-Merzbacher mouse model.

Prukop T, Epplen DB, Nientiedt T, Wichert SP, Fledrich R, Stassart RM, Rossner MJ, Edgar JM, Werner HB, Nave KA, Sereda MW.

Am J Hum Genet. 2014 Apr 3;94(4):533-46. doi: 10.1016/j.ajhg.2014.03.001. Epub 2014 Mar 27

 

A role for Schwann cell-derived neuregulin-1 in remyelination.

Stassart RM*, Fledrich R*, Velanac V, Brinkmann BG, Schwab MH, Meijer D, Sereda MW, Nave KA.

Nat Neurosci. 2013 Jan;16(1):48-54. doi: 10.1038/nn.3281. Epub 2012 Dec 9.

 

Murine therapeutic models for Charcot-Marie-Tooth (CMT) disease.

Fledrich R, Stassart RM, Sereda MW.

Br Med Bull. 2012 Jun;102:89-113. doi: 10.1093/bmb/lds010. Epub 2012 May 2. Review.

 

Lithium enhances remyelination of peripheral nerves.

Makoukji J, Belle M, Meffre D, Stassart RM, Grenier J, Shackleford G, Fledrich R, Fonte C, Branchu J, Goulard M, de Waele C, Charbonnier F, Sereda MW, Baulieu EE, Schumacher M, Bernard S, Massaad C.

Proc Natl Acad Sci U S A. 2012 Mar 6;109(10):3973-8. doi: 10.1073/pnas.1121367109. Epub 2012 Feb 21.

 

A rat model of Charcot-Marie-Tooth disease 1A recapitulates disease variability and supplies biomarkers of axonal loss in patients.

Fledrich R, Schlotter-Weigel B, Schnizer TJ, Wichert SP, Stassart RM, Meyer zu Hörste G, Klink A, Weiss BG, Haag U, Walter MC, Rautenstrauss B, Paulus W, Rossner MJ, Sereda MW.

Brain. 2012 Jan;135(Pt 1):72-87. doi: 10.1093/brain/awr322. Epub 2011 Dec 20.

 

The Wlds transgene reduces axon loss in a Charcot-Marie-Tooth disease 1A rat model and nicotinamide delays post-traumatic axonal degeneration.

Meyer zu Horste G, Miesbach TA, Muller JI, Fledrich R, Stassart RM, Kieseier BC, Coleman MP, Sereda MW.

Neurobiol Dis. 2011 Apr;42(1):1-8. doi: 10.1016/j.nbd.2010.12.006. Epub 2010 Dec 16.

 
Identification of the variant Ala335Val of MED25 as responsible for CMT2B2: molecular data, functional studies of the SH3 recognition motif and correlation between wild-type MED25 and PMP22 RNA levels in CMT1A animal models.

Leal A, Huehne K, Bauer F, Sticht H, Berger P, Suter U, Morera B, Del Valle G, Lupski JR, Ekici A, Pasutto F, Endele S, Barrantes R, Berghoff C, Berghoff M, Neundörfer B, Heuss D, Dorn T, Young P, Santolin L, Uhlmann T, Meisterernst M, Sereda MW, Stassart RM, Zu Horste GM, Nave KA, Reis A, Rautenstrauss B.

Neurogenetics. 2009 Oct;10(4):375-376
 

Brinkmann BG, Agarwal A, Sereda MW, Garratt AN, Müller T, Wende H, Stassart RM, Nawaz S, Humml C, Velanac V, Radyushkin K, Goebbels S, Fischer TM, Franklin RJ, Lai C, Ehrenreich H, Birchmeier C, Schwab MH, Nave KA.

Neuron. 2008 Aug 28;59(4):581-95. doi: 10.1016/j.neuron.2008.06.028.